Early Phase Research - First in Human
CRI Lifetree offers high-quality expertise and experience in the conduct of first in human studies involving the measurements of pharmacodynamic parameters. Our research organization is recognized as one of the largest Specialized Research Organizations (SRO) and Phase I service providers in the United States with an expanded Clinical Pharmacology capacity of over 190 beds.
Our Phase 1 team has performed more than 200 clinical studies, including First-in-Human (FIH) studies for biologics, reformulations and new chemical entities. In addition to measuring safety and pharmacokinetic parameters, we can provide expert advice on selecting the most appropriate pharmacodynamic evaluations for your compound. Our clinical research team is made up of the top professionals in the field who have a passion for their work and are truly committed to exceeding client expectations.
Accurate and well-interpreted pharmacodynamic data can expedite the subsequent evaluation of investigational drugs. By delivering science-driven solutions to phase I safety and pharmacologic questions, CRI Lifetree facilitates more confident decisions to accelerate product development.
- First in Human and First in Patient, Single Ascending Dose / Maximum Tolerated Dose
- Multiple Ascending Dose
- Full PK/PD collections in plasma, urine, and CSF
- Safety/tolerability, optimal dosing schedules and MTD in target populations
- Cardiac Safety (QTC) evaluations
- Abuse Liability Studies
- Drug-Drug Interactions
- Bioavailability/Bioequivalence Studies
- Dose Proportionality Studies
CRI Lifetree research centers have been strategically located in Marlton, NJ, Philadelphia, PA and Salt Lake City, UT as these are prime locations for safe and effective clinical studies. If you would like to schedule a consultation or receive further detail on our early phase research services, please contact the center nearest you. You can find complete contact information for your CRI Lifetree research center by clicking here to visit our contact page. We look forward to working with you to find the clinical solutions you need!